Melofen Plus Injection

-provides relief from fever & acute painful
inflammatory musculoskeletal disorders

Brand Name : Melofen Plus Injection

Composition :
Each ml contains
Meloxicam BP 5 mg
Paracetamol IP 150 mg
Lignocaine HCL IP 1% w/v
Benzyl Alcohol IP 2% w/v
Water for Injection IP q.s.
Mode of Action :

Melofen Plus is a combination of two powerful Drugs - Meloxicam & Paracetamol. Meloxicam is an Anti-inflammatory & Analgesic drug and Paracetamol is an Antipyretic drug with little Analgesic effect.

Meloxicam is a potent long-acting Non-steroidal Anti-Inflammatory Drug (NSAID) belonging to the Oxicam group of Drugs. It acts by inhibiting Prostaglandins synthesis, thereby exerting powerful Anti-inflammatory, Analgesic and Antipyretic effect. Meloxicam also has endo-toxic effect as it inhibits Thromboxane B2 which is responsible for vasoconstriction and platelet aggregation. Therefore, it ensures normal blood viscosity and smooth flow. Since Prostaglandins are the primary mediators of pain and inflammation, Meloxicam reduces the Prostaglandins level at the peripheral levels and provides as an excellent anti-inflammatory and analgesic effect- relief from pain, inflammation, and pyrexia.

Paracetamol is a centrally acting antipyretic and analgesic drug. It acts principally by inhibition of synthesis and release of Prostaglandin that mediate the effect of endogenous pyrogens in hypothalamus. It acts on the Hypothalamus to produce antipyresis and lowers the body temperature.

Lignocaine HCL is a local Anesthetic that helps in preventing the pain by blocking the signals at the nerve ending. Thus, there is no pain at the site of injection. Hence, the combined effect of all these is synergistic in nature and provides powerful Anti-inflammatory, Analgesic, and Antipyretic effect.



USPs
MELOFEN PLUS Injection
  • Provides relief from inflammation
  • Gives relief from distressing pain
  • Relaxes stiffened muscles
  • Improves mobility
  • Gives antipyretic effect
  • Offers dosage convenience due to its longer duration of action

Indication
  • In Pyretic Conditions (along with specific antibiotics)
    • Bacterial & viral Infections
    • Haemo-protozoan Infection
    • Ephemeral Fever (3 Days)
    • Pyrexia of unknown origin
  • Inflammatory conditions
    • Injury
    • Fractures
    • Lameness
    • Arthritis
    • Synovitis
    • Tendonitis
  • Painful conditions
    • Dehorning
    • Pre & post operative

Pre-cautions :
  • Do not administer concurrently with Gluco-corticosteroids or any other NSAIDS. In case of Horses, do not use in Mares during Pregnancy and lactation. For Cattle and Pigs, it can be safely given during pregnancy.

Recommended Dosage :
  • 0.5 mg. Meloxicam &10mg Paracetamol / Kg body weight

Presentation :
  • Vial 30 ml & 99ml

Melofen Plus Injection

 -provides relief from fever & acute painful inflammatory musculoskeletal disorders