-provides relief from fever & acute painful
inflammatory musculoskeletal disorders
|Each ml contains|
|Lignocaine HCL||IP||1% w/v|
|Benzyl Alcohol||IP||2% w/v|
|Water for Injection||IP||q.s.|
Melofen Plus is a combination of two powerful Drugs - Meloxicam & Paracetamol. Meloxicam is an Anti-inflammatory & Analgesic drug and Paracetamol is an Antipyretic drug with little Analgesic effect.
Meloxicam is a potent long-acting Non-steroidal Anti-Inflammatory Drug (NSAID) belonging to the Oxicam group of Drugs. It acts by inhibiting Prostaglandins synthesis, thereby exerting powerful Anti-inflammatory, Analgesic and Antipyretic effect. Meloxicam also has endo-toxic effect as it inhibits Thromboxane B2 which is responsible for vasoconstriction and platelet aggregation. Therefore, it ensures normal blood viscosity and smooth flow. Since Prostaglandins are the primary mediators of pain and inflammation, Meloxicam reduces the Prostaglandins level at the peripheral levels and provides as an excellent anti-inflammatory and analgesic effect- relief from pain, inflammation, and pyrexia.
Paracetamol is a centrally acting antipyretic and analgesic drug. It acts principally by inhibition of synthesis and release of Prostaglandin that mediate the effect of endogenous pyrogens in hypothalamus. It acts on the Hypothalamus to produce antipyresis and lowers the body temperature.
Lignocaine HCL is a local Anesthetic that helps in preventing the pain by blocking the signals at the nerve ending. Thus, there is no pain at the site of injection. Hence, the combined effect of all these is synergistic in nature and provides powerful Anti-inflammatory, Analgesic, and Antipyretic effect.
-provides relief from fever & acute painful inflammatory musculoskeletal disorders